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Table 2 Study outcome measures and corresponding questionnaires

From: Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer: design of a multicenter, randomized controlled trial

Variable

Questionnaire

Details

Primary outcomes

 

Sexual functioning

SAQ [88,89]

• Assesses sexual functioning

• 10 items; 4-point Likert scales

• Subscales: pleasure; discomfort; habit

• Subscale scores: pleasure 0-18; discomfort 0-6; habit 0-3; higher score indicates higher levels of pleasure; lower score indicates lower levels of discomfort; habit is a single item (0 ‘less sexual activity than usual’ to 3 ‘much more sexual activity than usual’)

• Time frame: past month

• Test retest kappa: 0.50-0.76

 

FSFI [86,90]

• Assesses sexual functioning

• 19 items; 5- and 6-point Likert scales

• Subscales: desire; arousal; lubrication; orgasm; satisfaction; pain

• Total score*: 2-36/Subscale scores*: desire 1.2-6; arousal 0-6; lubrication 0-6; orgasm 0-6; satisfaction 0.8-6; pain 0-6; higher score indicates better sexual functioning

• Time frame: past 4 weeks

• Cronbach’s alpha: >0.82

 

FSDS-R [91,99]

• Assesses distress related to sexual dysfunction

• 13 items; 5-point Likert scale (0 ‘never’ to 4 ‘always’)

• Total score: 0-52; higher score indicates higher level of sexual distress

• Time frame: past 30 days

• Cronbach’s alpha: >0.88

Intimacy

PAIR Inventory [87]

• 36 items; 5-point Likert scale (0 ‘strongly disagree’ to 4 ‘strongly agree’)

• Subscales: emotional intimacy; social intimacy; sexual intimacy; intellectual intimacy; recreational intimacy; conventionality

• Subscale score*: 0-96; higher score indicates higher levels of intimacy

• Time frame: ‘how the relationship is now’

• Cronbach’s alpha: 0.70-0.80

Secondary outcomes

 

Body image

QLQ-BR23 Body Image subscale [92]

• 4 items; 4-point Likert scale (1 ‘not at all’ to 4 ‘very much’)

• Score: 0-100; higher score indicates higher level of functioning

• Time frame: past week

• Cronbach’s alpha: 0.69-0.91

Menopausal symptoms

FACT-ES ESS-18 [93]

• 18 items; 5-point Likert scale (0 ‘not at all’ to 4 ‘very much’)

• Score range: 0-72; higher score indicates fewer menopausal symptoms

• Time frame: past 7 days

• Cronbach’s alpha = 0.79

Marital functioning

MMQ [84]

• 20 items; 9-point Likert scale (range 0-8)

• Scales: marital adjustment (M); sexual adjustment (S); general life adjustment (GL)

• Scale scores*: S + GL: 0-40; M: 0-80; higher score indicates greater dissatisfaction in the specific domain

• Time frame: past 2 weeks

• Cronbach’s alpha in normal vs. distressed group: M = 0.88/0.87; S = 0.64/0.82; GL = 0.60/0.68

Psychological distress

HADS [94,95]

• 14 items; 4-point Likert scale (range 0-3)

• Subscales: depression (HADS-D); anxiety (HADS-A)

• Total score: 0-42/Subscale scores: 0-21; higher score indicates more psychological distress

• Time frame: past week

• Cronbach’s alpha: HADS-A: 0.68-0.93; HADS-D: 0.67-0.90

Health-related quality of life

SF-36 [96,97]

• 36 items; dichotomous and 3- to 6-point Likert scales

• Subscales: physical functioning; role limitations due to physical health problems; bodily pain; social functioning; general mental health; role limitations due to emotional problems; vitality; general health perceptions

• Subscale score*: 0-100; higher score indicates higher levels of functioning/well-being

• Time frame: past week

• Cronbach’s alpha = 0.66-0.93 (mean: 0.84)

Sexual functioning (male partners)

IIEF [85]

• 15 items; 5-/6-point Likert scale (0-5 or 1-5)

• Subscales: erectile function (EF); orgasmic function (OF); sexual desire (SD); intercourse satisfaction (IS); overall satisfaction (OS)

• Total score: 5-75/Subscale scores: EF 1-30; OF 0-10; SD 2-10; IS 0-15; OS 2-10; higher score indicates a higher level of functioning in specific domain

• Time frame: past 4 weeks

• Cronbach’s alpha: 0.73-0.99

  1. *The score is calculated based on weighted items.
  2. FACT-ES ESS-18 = Functional Assessment of Cancer Treatment-Endocrine Symptoms, Endocrine Symptom Subscale; FSDS = Female Sexual Distress Scale; FSFI = Female Sexual Function Index; HADS = Hospital Anxiety and Depression Scale; IIEF = International Index of Erectile Function; MMQ = Maudsley Marital Questionnaire; PAIR Inventory = Personal Assessment of Intimacy in Relationships Inventory; QLQ-BR23 = EORTC breast cancer-specific quality of life questionnaire; SAQ = Sexual Activity Questionnaire; SF-36 = 36-Item Short Form Health Survey.