| All studies: Overexpressed in sensitive cells |  |  | Overexpressed in resistant cells |  |
---|---|---|---|---|---|
 | Term | p-value |  | Term | p-value |
Table 2a | |||||
O | Pathways in cancer | 4.9E-15 | T | positive regulation of biosynthetic process | 3.6E-17 |
MM | plasma membrane part | 7.7E-12 | T | positive regulation of cellular biosynthetic process | 5.2E-17 |
CC | regulation of cell proliferation | 1.3E-10 | T | positive regulation of macromolecule Metabolic process | 2.3E-16 |
MM | endomembrane system | 1.4E-10 | R | response to endogenous stimulus | 8.9E-16 |
MM | cell fraction | 2.1E-09 | T | positive regulation of nitrogen compound Metabolic process | 1.6E-15 |
A | regulation of cell death | 2.2E-09 | T | positive regulation of macromolecule biosynthetic process | 9.3E-15 |
A | regulation of programmed cell death | 2.6E-09 | CC | regulation of cell proliferation | 4.9E-14 |
Mt | positive regulation of macromolecule Metabolic process | 2.6E-09 | R | response to hormone stimulus | 6.9E-14 |
CC | cell proliferation | 5.7E-09 | R | response to organic substance | 9.6E-14 |
T | protein complex biogenesis | 7.0E-09 | CC | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid Metabolic process | 1.2E-13 |
Table 2b | |||||
A | negative regulation of cell death | 1.4E-07 | A | regulation of apoptosis | 3.3E-10 |
AD | cell migration | 5.0E-08 | A | negative regulation of apoptosis | 4.1E-10 |
AD | cell adhesion | 2.3E-07 | A | anti-apoptosis | 8.1E-08 |
AD | localization of cell | 1.2E-06 | CC | cell cycle | 8.2E-06 |
AD | cell projection | 3.2E-06 | CC | regulation of cell size | 3.4E-05 |
AD | Focal adhesion | 4.3E-05 | CY | cytoskeletal protein binding | 3.2E-06 |
CC | negative regulation of cell proliferation | 9.0E-05 | CY | actin cytoskeleton | 1.0E-04 |
CC | regulation of DNA Metabolic process | 1.5E-04 | DF | negative regulation of cell differentiation | 6.1E-06 |
CC | mitotic cell cycle | 5.9E-04 | E | regulation of oxidoreductase activity | 5.1E-05 |
CC | regulation of cell size | 6.4E-04 | E | positive regulation of oxidoreductase activity | 4.2E-04 |
IM | response to wounding | 4.4E-05 | IM | immune system development | 1.8E-09 |
IM | immune system development | 6.2E-04 | IM | response to wounding | 2.4E-08 |
IM | T cell activation | 6.8E-04 | IM | regulation of cytokine production | 1.1E-07 |
IM | humoral immune response | 8.4E-04 | IM | positive regulation of immune system process | 4.3E-06 |
M_c | oligosaccharide Metabolic process | 7.0E-04 | IM | positive regulation of cell activation | 2.6E-05 |
M_l | regulation of lipid Metabolic process | 6.8E-06 | IM | inflammatory response | 2.8E-05 |
M_l | phosphoinositide Metabolic process | 7.3E-05 | IM | wound healing | 1.6E-04 |
M_l | positive regulation of lipid Metabolic process | 1.0E-04 | IM | immune response | 1.8E-04 |
M_l | lipid biosynthetic process | 1.1E-04 | IM | defense response | 4.5E-04 |
M_l | phospholipid Metabolic process | 2.3E-04 | IM | regulation of production of molecular mediator of immune response | 9.1E-04 |
M_l | cellular lipid catabolic process | 4.2E-04 | M_c | monosaccharide Metabolic process | 4.3E-06 |
M_l | glycerolipid Metabolic process | 5.4E-04 | M_c | hexose Metabolic process | 1.2E-05 |
M_l | glycerophospholipid Metabolic process | 7.0E-04 | M_c | glucose Metabolic process | 5.8E-05 |
M_l | lipoprotein particle clearance | 9.2E-04 | M_c | regulation of cellular ketone Metabolic process | 2.0E-04 |
O | Oncogenesis | 3.4E-05 | M_l | regulation of lipid Metabolic process | 2.6E-07 |
O | ErbB signaling pathway | 4.2E-04 | M_l | regulation of lipid biosynthetic process | 1.1E-04 |
O | Wnt signaling pathway | 7.7E-04 | M_l | regulation of fatty acid Metabolic process | 4.2E-04 |
 |  |  | M_l | positive regulation of lipid Metabolic process | 4.9E-04 |
Legend: | Â | Â | MO | regulation of cell motion | 2.8E-12 |
A | Apoptosis | Â | O | Pathways in cancer | 2.8E-10 |
AD | Adhesion | Â | O | regulation of DNA Metabolic process | 1.2E-04 |
CC | Cell cycle | Â | O | Ras protein signal transduction | 2.1E-04 |
CY | Cytoskeleton | Â | O | Oncogenesis | 4.0E-04 |
DF | Differentiation | Â | R | response to steroid hormone stimulus | 6.2E-12 |
E | Energy | Â | R | response to insulin stimulus | 1.5E-07 |
Mt | Metabolism | Â | R | response to vitamin | 1.2E-06 |
IM | Immunity | Â | R | response to lipopolysaccharide | 1.8E-06 |
M_c | Metabolism-carbohydrates | Â | R | response to glucocorticoid stimulus | 2.6E-06 |
M_l | Metabolism-lipids | Â | R | response to hydrogen peroxide | 1.4E-05 |
MM | Membrane | Â | R | cellular response to stress | 3.1E-05 |
MO | Motility | Â | V | regulation of angiogenesis | 4.6E-06 |
O | Oncogenesis | Â | V | myeloid leukocyte activation | 4.4E-05 |
R | Response to stimuli | Â | V | positive regulation of angiogenesis | 4.2E-04 |
T | Transcription/translation | Â | Â | Â | Â |
V | Vasculogenesis | Â | Â | Â | Â |
Sensitive | Resistant | ||||
Table 2c | Â | ||||
ErbB Signalling pathway | Ras protein signal transduction | ||||
BCL2-associated agonist of cell death | v-ral oncogene homolog A | ||||
mitogen-activated protein kinase 9 | FERM, RhoGEF and pleckstrin domain | ||||
phosphoinositide-3-kinase beta | nischarin | ||||
glycogen synthase kinase 3 beta | IGF1 (somatomedin C) | ||||
c-abl oncogene 1 | Rho GTPase activating protein 6 | ||||
v-crk sarcoma virus CT10 | X-associated ankyrin-containing protein | ||||
mitogen-activated protein kinase 8 | ras homolog gene family, member A | ||||
ribosomal protein S6 kinase | myosin IXB | ||||
mitogen-activated protein kinase 10 | mitogen-activated protein kinase 1 | ||||
phosphoinositide-3-kinase alpha | GRB2-related adaptor protein 2 | ||||
phospholipase C, gamma 1 | Rho GTPase activating protein 5 | ||||
CDK inhibitor 1A (p21, Cip1) | soc-2 suppressor of clear homolog | ||||
epiregulin | mitogen-activated protein kinase 14 | ||||
v-myc oncogene homolog | ropporin, rhophilin associated protein 1B | ||||
phosphoinositide-3-kinase subunit 5 | r-ras oncogene homolog | ||||
v-erb-b2 oncogene homolog 2 | CDC42 effector protein | ||||
v-aktoncogene homolog 1 | fibroblast growth factor 2 (basic) | ||||
calcium/calmodulin-dep. protein kinase II | G protein alpha 12 | ||||
protein kinase C, alpha | parathyroid hormone | ||||
neuregulin 1 | GRB2-related adaptor protein | ||||
NCK adaptor protein 1 | muscle RAS oncogene homolog | ||||
PTK2 protein tyrosine kinase 2 | WAS protein family, member 2 | ||||
phosphoinositide-3-kinase delta | SHC transforming protein 1 | ||||
betacellulin | MAPKAP 2 | ||||
ribosomal protein S6 kinase 2 | Rho guanine nucleotide exchange factor 3 | ||||
jun oncogene | ATP-binding cassette, member 1 | ||||
p21 (Cdc42/Rac)-activated kinase 2 | cofilin 1 (non-muscle) | ||||
translation initiation factor 4E binding | CDC42 effector protein 4 | ||||
phospholipase C, gamma 2 | neurofibromin 1 | ||||
 | neurotrophic tyrosine kinase, type 1 | ||||
 | ral GDF stimulator-like 2 | ||||
 | linker for activation of T cells | ||||
Sensitive | Resistant | ||||
Table 2d | Â | ||||
Complement System | |||||
complement component 2 | complement component 1, q A chain | ||||
complement component 3a receptor 1 | complement component 1, q B chain | ||||
complement component 7 | complement factor H | ||||
complement component 8, alpha | Â | ||||
complement component 8, beta | Â | ||||
complement component 9 | Â | ||||
complement factor B | Â | ||||
complement factor H | Â | ||||
complement factor I | Â | ||||
Chemokines | |||||
chemokine (C-C motif) ligand 2 | chemokine (C-C motif) ligand 13 | ||||
chemokine (C-C motif) ligand 22 | chemokine (C-C motif) ligand 19 | ||||
chemokine (C-C motif) ligand 23 | chemokine (C-C motif) ligand 2 | ||||
chemokine (C-C motif) ligand 24 | chemokine (C-C motif) ligand 20 | ||||
chemokine (C-C motif) receptor 5 | chemokine (C-C motif) ligand 8 | ||||
 | chemokine (C-C motif) receptor 5 | ||||
 | chemokine (C-X-C motif) ligand 1 | ||||
 | chemokine (C-X-C motif) ligand 13 | ||||
 | chemokine (C-X-C motif) ligand 6 | ||||
Interleukins | |||||
interleukin 1, alpha | interleukin 1 family, member 6 | ||||
interleukin 10 | interleukin 1, alpha | ||||
interleukin 2 receptor, alpha | interleukin 1, beta | ||||
interleukin 6 (interferon, beta 2) | interleukin 10 | ||||
interleukin 8 | interleukin 10 receptor, beta | ||||
 | interleukin 13 | ||||
 | interleukin 22 | ||||
 | interleukin 5 | ||||
 | interleukin 6 (interferon, beta 2) | ||||
 | interleukin 9 |