Figure 2

Internalization of the GMBP1 peptide into SGC7901/ADR and SGC7901/VCR cells. (A): Relative expression of GRP78 in SGC7901/ADR cells and SGC7901/VCR cells transfected with control-siRNA or GRP78-siRNA, which were confirmed western blot analysis. The values represent the means from three separate experiments, and the error bars represent the SEM (*P < 0.01). (B): The relative mRNA level of GRP78 in SGC7901/ADR and SGC7901/VCR cells. (C, D): a, d, g, j: The cytoplasmic localization of FITC-GMBP1 (green). b, e, h, k: Nuclear staining with 4, 6-diamidino-2-phenylindole (DAPI; blue). c, f, i, l: Merged images showing the relationship between GMBP1 and the nucleus.