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Table 1 Expression levels of epithelial and mesenchymal markers in breast cancer cell lines and CTCs

From: Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic breast cancer

 

Keratin

vimentin

vim/K

MCF-7

Range

25.08 -131.69

9.01 – 24.75

0.12 - 0.49

Mean

87.34 ± 18.99

15.68 ± 2.58

0.19 ± 0.05

T47D

Range

15.49 -80.36

2.80 -16.27

0.17 – 0.43

Mean

35.43 ± 10.62

6.73 ± 2.16

0.19 ± 0.07

MDA.MB231

Range

4.22 -39.12

13.77 – 72.70

1.19 – 10.88

Mean

11.47 ± 4.87

43.38 ± 12.06

4.44 ± 1.98

Hs578T

Range

1.73-7.40

12.30 -153.80

5.47 – 38.88

Mean

4.02 ± 1.00

53.64 ± 24.81

13.14 ± 5.08

MCF-7 EGF

Range

7.59 – 43.06

11.79 – 52.23

0.45 – 5.05

Mean

18.37 ± 7.56

23.63 ± 9.10

1.57 ± 1.02

CTCs

Range

1.49 – 213.19

0.00 - 155.24

0.00 – 22.46

Mean

30.06 ± 25.00

26.42 ± 25.45

1.62 ± 3.96

  1. The range and mean values (± SD) were calculated by measuring the fluorescence intensity (CTCF/area) of each marker. For the calculation of vim/K ratios, data were obtained from double staining (Keratin and vimentin) immunofluorescence experiment.
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BMC Cancer

ISSN: 1471-2407

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