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Table 2 Distribution of the STAT3 rs744166 genotypes according to the gender, mean age, H. pylori status and CagA status in blood donors (n = 541)

From: STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

 

Gender

STAT3 genotypes

 

Female

Male

AA

AG

GG

Total

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

Female

132 (24.4)

-

39 (29.5)

63 (47.8)

30 (22.7)

132 (100)

Male

-

409 (75.6)

142 (34.7)

187 (45.7)

80 (19.6)

409 (100)

total

-

-

181 (33.5)

250 (46.2)

110 (20.3)

541 (100)

Mean age in yrs (SD)

33.6 (9.9)

33.8 (9.6)

34.6 (10.3)

33.6 (9.8)

32.9 (9.8)

33.8 (10.0)

Range yrs

18 - 59

18 - 65

18 - 65

18 - 64

19 - 59

18 - 65

Hp -ve

53 (40.2)

118 (28.9)

53 (29.3)

81 (47.4)

37 (21.6)

171 (31.6)

Hp +ve

79 (59.8)

291 (71.1)

128 (34.6)

169 (45.7)

73 (19.7)

370 (68.4)

CagA -ve

34 (43.0)

126 (43.3)

51 (31.9)

77 (48.1)

32 (20.0)

160 (43.3)

CagA +ve

45 (57.0)

165 (56.7)

73 (34.8)

95 (45.2)

42 (20.0)

210 (56.7)

  1. n, number; SD, standard deviation; yrs, years; Hp, Helicobacter pylori; -ve, negative; +ve, positive