Table 5 Pathway analysis of genetic changes in A2780 and A2780cis in response to hypoxia

A2780

MAPK signalling

0.001

Up-Regulated

Focal adhesion

0.002

Renal Cell Carcinoma

0.01

Starch and Sucrose Metabolism

0.04

Complement and Coagulation Cascade

0.04

A2780cis

MAPK signalling

0.02

Focal adhesion

<0.001

Axon guidance

0.002

TGF beta signalling

0.007

Toll like receptor signalling

0.02

DNA replication

<0.001

A2780

Cell cycle

<0.001

Down-regulated

Pyrimidine metabolism

<0.001

Base Excision Repair

<0.001

Homologous Recombination

<0.001

DNA replication

<0.001

A2780cis

Cell cycle

<0.001

Pyrimidine metabolism

0.001

Base excision repair

0.004

Oxidative phosphorylation

<0.001