Table 3 TWIST1 expression in tumor cells and tumor stroma

All

102

8.6

2.2

NA

40.6

4.2

NA

T-stage

 1

64

7.7

2.8

0.05

48.7

5.1

0.0007

 >1

38

10.1

3.6

26.0

6.8

N-stage

 0

60

9.5

2.9

0.87

44.3

5.4

0.09

 >1

42

7.3

3.4

35.0

6.6

Grade

 1 and 2

60

10.2

2.9

0.35

38.7

5.6

0.86

 3

40

6.6

3.5

43.6

6.7

Histology

 IDC

85

9.0

2.4

0.25

44.2

4.5

0.06

 Other

17

6.8

5.4

22.5

10.1

Hormone receptor status

 Negative

16

1.8

5.9

0.23

36.8

11.0

0.53

 Positive

86

9.7

2.4

41.2

4.6

HER2 status

 Positive

16

17.8

5.4

0.74

42.5

10.3

0.75

 Negative

86

6.8

2.4

40.2

4.6

Ki 67 (cut-off 14 %)

 Low

51

9.1

3.1

0.83

39.0

5.9

0.60

 High

51

8.1

3.2

42.2

6.0

Epithelial CTC

 Present

12

4.2

6.4

0.96

43.3

11.9

0.75

 Absent

90

9.2

2.4

40.2

4.5

EMT CTC

 Present

16

7.8

5.5

0.62

42.2

10.3

0.98

 Absent

86

8.7

2.4

40.3

4.6

Any CTC

 Present

25

6.2

4.4

0.71

44.6

8.2

0.68

 Absent

77

9.4

2.6

39.1

4.9