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Fig. 3 | BMC Cancer

Fig. 3

From: Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4

Fig. 3

Effect of miR-10b levels on apoptosis-induction and invasion. Effect of miR-10b levels on apoptosis-induction in (a) MCF-7 and (b) MCF7TR cells. Induction of apoptosis was assessed by DNA Histone-ELISA assay. Invasion of (c) MCF-7 and (d) MCF7TR cells was assessed by plating cells in matrigel-coated plates MCF-7, non-specific pre-miRNAs transfected MCF-7 cells; MCF-7 + pre-miR-10b, pre-miR-10b transfected MCF-7 cells; MCF7TR, non-specific anti-miRNAs transfected MCF7TR cells; MCF7TR + anti-miR-10b, anti-miR-10b transfected MCF7TR cells.

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BMC Cancer

ISSN: 1471-2407

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