Fig. 1
From: Immunohistochemical evaluation of ROCK activation in invasive breast cancer
Examples of ROCKII S1366 phosphorylation immunohistochemical staining in breast carcinomas. Breast carcinoma cases varied greatly in ROCKII S1366 phosphorylation. a, dA grade-2 invasive ductal carcinoma with negative signal; (b, e) a metastatic ductal carcinoma in axillary lymph node showing significant positive signal in nuclei; (c, f) a grade-2 invasive ductal carcinoma with cytosol and nuclear positive signal. D-F shows enlargements of the boxed regions in A-C. Scale bars, 20 μm