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Table 2 The results from ROCK phosphorylation staining, stratified by tumor types

From: Immunohistochemical evaluation of ROCK activation in invasive breast cancer

Tumor type

Cytoplasmic staining

Nuclear staining

Negative/weak

Moderate

Strong

P a

Mean %

(Standard deviation)

P b

ROCKII S1366 phosphorylation

 CIS

52 (93 %)

4 (7 %)

0 (0 %)

] 0.886

] 0.814

6.9 (16.4)

] 0.329 ] 0.003

 IC

107 (92 %)

9 (8 %)

0 (0 %)

8.7 (20.7)

 ICM

91 (88 %)

12 (12 %)

0 (0 %)

20.8 (29.6)

ROCKI S1333 phosphorylation

 CIS

50 (89 %)

5 (9 %)

1 (2 %)

] 0.433

] 0.450

1.3 (5.1)

] 0.908

] 0.933

 IC

96 (83 %)

19 (17 %)

0 (0 %)

0.9 (3.8)

 ICM

86 (83 %)

16 (16 %)

1 (1 %)

2.1 (8.4)

  1. Data presented as number (%) for cytoplasmic staining and mean % (Standard deviation) for nuclear staining. Bold values indicate statistical significance (P < 0.05)
  2. CIS, Carcinoma in situ; IC, Invasive carcinoma; ICM, Invasive carcinoma with metastasis. aChi-square test for trend. bMann-Whitney test