From: Immunohistochemical evaluation of ROCK activation in invasive breast cancer
Tumor type | Cytoplasmic staining | Nuclear staining | ||||
---|---|---|---|---|---|---|
Negative/weak | Moderate | Strong | P a | Mean % (Standard deviation) | P b | |
ROCKII S1366 phosphorylation | ||||||
 CIS | 52 (93 %) | 4 (7 %) | 0 (0 %) | ] 0.886 ] 0.814 | 6.9 (16.4) | ] 0.329 ] 0.003 |
 IC | 107 (92 %) | 9 (8 %) | 0 (0 %) | 8.7 (20.7) | ||
 ICM | 91 (88 %) | 12 (12 %) | 0 (0 %) | 20.8 (29.6) | ||
ROCKI S1333 phosphorylation | ||||||
 CIS | 50 (89 %) | 5 (9 %) | 1 (2 %) | ] 0.433 ] 0.450 | 1.3 (5.1) | ] 0.908 ] 0.933 |
 IC | 96 (83 %) | 19 (17 %) | 0 (0 %) | 0.9 (3.8) | ||
 ICM | 86 (83 %) | 16 (16 %) | 1 (1 %) | 2.1 (8.4) |