Table 3 Univariate Cox regression analysis of baseline patient characteristics

Gender

  Male/Female

1.2

0.80–2.11

0.30

Age

0.99

0.97–1.02

0.75

Performance status

  0/1

1.24

0.84–1.83

0.26

Clinical stage

  IIIA/IIIB

1.92

1.30–2.85

<0.001

Histology

  Ad/Non-ad

0.74

0.50–1.09

0.13

  Sq/Non-sq

1.19

0.79–1.76

0.37

Smoking history

  Yes/No

1.39

0.82–2.25

0.19

Diabetes Mellitus

  Yes/No

1.66

1.01–2.63

0.04

Body mass index (BMI) (kg/m²)

  BMI < 18.5 / 18.5 ≤ BMI < 25

1.54

0.77–2.78

0.20

  25 ≤ BMI < 30 + BMI ≥ 30/18.5 ≤ BMI < 25

0.95

0.55–1.55

0.85

Laboratory parameters

  White blood cell count

1

0.99–1.00

0.63

  Hemoglobin

0.85

0.76–0.94

0.003

  Albumin

0.4

0.26–0.62

<0.001

  AST

1.01

0.99–1.03

0.22

  ALT

1

0.99–1.02

0.33

  LDH

1

1.00–1.05

0.01

  Calcium

0.81

0.49–1.35

0.43

  Creatinine

1.24

0.37–3.88

0.71

  Glucose

0.99

0.98–1.00

0.37