Table 4 Multivariate adjusted odds ratios (OR) and 95 % confidence intervals (CI) of HER2-positive and HER2-negative invasive cancer associated with caspase-8 polymorphisms

rs12693932

1.111

0.879

1.404

1.110

0.870

1.410

1.123

0.983

1.281

1.150

1.000

1.320

rs6745051

1.148

0.908

1.450

1.150

0.900

1.460

1.095

0.959

1.249

1.120

0.980

1.280

rs3769825

1.153

0.915

1.455

1.180

0.930

1.490

1.164

1.020

1.327

0.024

1.200

1.050

1.370

0.008

rs11899004

1.680

1.259

2.241

0.0004

1.620

1.210

2.180

0.0014

1.118

0.930

1.344

1.130

0.940

1.360

rs6736233

1.959

1.332

2.881

0.001

1.890

1.270

2.810

0.0017

1.283

0.995

1.655

1.290

0.990

1.670

rs1861270

0.983

0.758

1.275

1.050

0.800

1.370

1.098

0.952

1.268

1.150

0.990

1.330

rs6723097

1.336

1.057

1.688

0.015

1.410

1.110

1.800

0.0055

1.170

1.025

1.337

0.020

1.220

1.070

1.400

0.004

rs2293554

1.945

1.341

2.822

0.001

1.980

1.340

2.920

0.0005

1.165

0.910

1.490

1.200

0.930

1.550

rs1045485

0.852

0.572

1.268

0.810

0.540

1.220

1.072

0.872

1.317

1.030

0.830

1.270

rs1035140

0.958

0.760

1.207

1.000

0.790

1.270

1.081

0.950

1.231

1.100

0.970

1.260

rs700636

1.012

0.802

1.276

1.080

0.850

1.380

1.076

0.944

1.226

1.110

0.970

1.270

rs1679181

1.048

0.831

1.323

0.990

0.780

1.260

0.910

0.798

1.039

0.890

0.780

1.020