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Table 2 Summary of treatment exposure

From: Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a randomized, double-blind safety study comparing cetuximab produced from two manufacturing processes using the EXTREME study regimen

Treatment exposure

US commercial cetuximab

Arm A

(N = 77)

BI-manufactured cetuximab

Arm B

(N = 71)

Median duration of treatment (25th percentile, 75th percentile), weeks

  

 Cetuximab

12.4 (6.0, 18.0)

13.6 (6.0, 20.0)

 Cisplatin

6.9 (3.0, 14.0)

9.0 (3.0, 18.0)

 Carboplatin

12.6 (6.1, 18.0)

15.0 (7.0, 20.0)

 5-FU

13.0 (6.0, 17.9)

13.0 (6.3, 20.0)

Relative dose intensity, %

  

 Cetuximab

87.5

87.1

 Cisplatin

86.8

87.9

 Carboplatin

94.3

88.4

 5-FU

84.1

82.9

  1. Abbreviations: 5-FU 5-fluorouracil, BI Boehringer Ingelheim, US United States