Fig. 4

Distribution of CD4+, CD8+, and CD20+ cells in Kenyan breast cancer tissue samples. a Data analysis comparing the not cancer and cancer samples stained for T helper cell presence using a CD4 antibody. Significant increase was seen in T helper cell infiltration in the cancer samples shown by a higher percentage of CD4+ stained cell area (P = 0.03; Mann-Whitney). b Data analysis comparing noncancerous and cancerous samples stained for CD8+ cytotoxic T cells. No significant difference was seen in cytotoxic T cell infiltration in the cancerous samples, as shown by percentage of positively stained cell area (n.s.; Mann-Whitney). c Data analysis comparing the noncancerous to the cancerous samples stained for CD20+ B cells. No significant difference was seen in CD20+ cell infiltration in the cancerous samples, as shown by percentage of CD20+ stained cell area (n.s.; Mann-Whitney). d Immunohistochemistry of CD4, CD8, and CD20 in representative cancer and not cancer tissue samples.Because the graphs are log scale, any samples with unstained sections (i.e., zero) are not included in the graph. The bar represents the median of all samples in the indicated cohort and includes any unstained samples