Fig. 1
From: Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer
Detailed characterization of synthesized NCe-FA. a High resolution transmission electron microscopy image of the NCe-FA showed particles sized 8–10 nm. b The hydrodynamic size of the nanoparticles showed slight agglomeration of the particles in cell culture medium, 76 % of particles in the range between 20 and 70 nm. c X-Ray T spectrum shows the crystalline property of the nanoparticles. d X-ray photoelectron spectroscopy spectra of nitrogen 1S of NCe, NCe-EPH and NCe-EPH-FA confirms the presence of folic acid on the surface of the nanoparticles. e X-ray photoelectron spectroscopy spectra of Ce3d of NCe, NCe-APTMS and NCe-APTMS-FA showed no significant change in surface chemistry (Ce3+/Ce4+) due to modification of the surface. f Thermogravimetric analysis weight loss spectra for NCe-APTMS and NCe-APTMS-FA showed presence of folic acid on the surface of the NCe nanoparticle