Fig. 6
From: Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer
NCe-FA enhances apoptosis and ROS in combination with cisplatinum. a Representative caspase-3 staining of the tumor tissue, indicating cells undergoing apoptosis and b 4 hydroxynonenal, indicating presence of oxidative stress, from various treatment groups (200×). Expression was visualized as a positive brown stain. Each stained picture is representative of at least 5 different fields examined from 3 individual slides stained per group. Quantification of the stain was performed on a scale of 0–3; 0–1 for no or weak stain; 2 for moderate stain and 3 for strong stain. Average score is represented as a respective bar graph. *p < 0.001, *p < 0.05