Table 1 Characteristics and outcomes of medical patients with advanced solid cancer in the ICU
Variables | N (%) or median (25th-75th percentile) |
|---|---|
Age | 63 (54–74) |
Sex (male) | 87 (61.7 %) |
Chronic health status | |
Diabetes mellitus | 57 (40.4 %) |
Chronic heart failure | 48 (34 %) |
Hypertension | 48 (34 %) |
Chronic renal failure | 0 (0) |
Chronic bronchitis | 6 (4.3 %) |
Types of solid cancer | |
Stomach cancer | 33 (23.4 %) |
Pancreas cancer | 19 (13.5 %) |
Lung cancer | 15 (10.6 %) |
Rectal cancer | 10 (7.1 %) |
Colon cancer | 10 (7.1) |
Esophageal cancer | 6 (4.3 %) |
Breast cancer | 6 (4.3 %) |
others | 42 (29.8 %) |
History of antitumor therapy | |
Surgery | 123 (87.2 %) |
Chemotherapy | 72 (51.1 %) |
radiotherapy | 18 (12.8 %) |
biological therapy | 6 (4.3 %) |
KPS | |
Admit to hospital | 80 (50–90) |
Admit to ICU | 10 (10–10) |
Intervention time (hours) | 3 (2–12) |
Major reasons for ICU | |
Respiratory failure | 54 (38.3 %) |
Severe sepsis or septic shock | 39 (27.7 %) |
Acute renal failure | 12 (8.5 %) |
Acute heart failure | 18 (12.8 %) |
ICU therapeutic interventions | |
vasopressors | 60 (42.6 %) |
mechanical ventilation | 81 (57.4 %) |
renal replacement therapy | 15 (10.6 %) |
APCHE II score | |
Day 1 | 21 (18–28) |
Day 3 | 14 (11–20) |
Day 7 | 12 (10–15) |
SOFA score | |
Day 1 | 9 (5–13) |
Day 3 | 5 (3–9) |
Day 7 | 4 (2–7) |
Outcomes | |
Length of ICU stay (days) | 6 (3–10) |
ICU mortality | 21 (14.9 %) |
In-hospital mortality | 42 (29.8 %) |
Overall survival (month) | 17 (4–27) |