Fig. 1From: Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcomaAnalysis of total MMP activity in osteosarcoma biopsies by in situ zymography. Green fluorescent areas represent MMP mediated degradation of FITC-labeled substrate. Representative in situ zymographies of cryosections derived from (a) good responder and (b) poor responder are shown. Yellow frames indicate the area of magnification shown in (c) and (d). DAPI counterstain of nuclei is shown in blueBack to article page