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Fig. 1 | BMC Cancer

Fig. 1

From: Down-regulation of S100A9 inhibits osteosarcoma cell growth through inactivating MAPK and NF-κB signaling pathways

Fig. 1

The expression of S100A9 was found in tissue microarrays. a. The immunohistochemical analysis of S100A9 expression was performed in 120 human osteosarcoma samples and 40 normal bone samples. Representative cases of OS different grades were shown. b. Statistical quantification of SI in normal bone tissues and different grades of OS issues (*p < 0.05, ***p < 0.001, versus normal bone tissues; ###p < 0.001, versus OS Grade III). c. The mRNA levels of S100A9 were tested by real-time Quantitative PCR in osteosarcoma tissues and normal bone tissues (n = 3, **p < 0.01, ***p < 0.001, versus normal bone group; ##p < 0.001, versus OS Grade III). d. The protein levels of S100A9 were tested in three fresh osteosarcoma tissues and normal bone tissue. Tumor 1 and tumor 2 belonged to grade I, tumor 3 belonged to grade III. e. Relationship between overall survival and level of S100A9 expression (n = 120, p < 0.05)

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BMC Cancer

ISSN: 1471-2407

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