Fig. 3

Knockdown of S100A9 gene inhibits OS growth in vivo. a. General observation of tumor xenografts in OS cells between empty vectors groups (group2, left) and siRNA-S100A9 vectors groups (group3, right). b. The volumes of tumor xenografts in OS cells were measured on a weekly basis and tumor growth curves were plotted (n = 5, ^**p < 0.01; ^***p < 0.001, versus empty vectors group). c. The mice were killed at 28 days and the tissues xenograft tumors were collected to determine the PCNA and Ki67 index (^**p < 0.01;^***p < 0.001, versus empty vectors group)