From: 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response
A (BT474): Ki67 antigen staining- expressed as % control
C
H
T
F
H + T
H + F
3D
100
106
70
27
6
2D
33
62
25
2
B (MDAMB361): Ki67 antigen staining- expressed as % control
75
5
9
64