Fig. 2
Co-RNAi of uPAS components and of IGF1R significantly reduces malignancy of BT549 and MDA-MB-231 cells. a Representative immunoblottings of uPAR, uPA (supernatant), IGF1R, GAPDH, (phospho) c-Met, MMP2, (phospho) 44/42 MAPK and p27Kip1 are shown. Tubulin was used as loading control. b WST-1 assay was conducted 48 h (n = 5), c Scratch wound assays 24 h and 48 h (n = 3), d Matrigel invasion assays were conducted 48 h after starting the experiment (n = 3). The quantifications were determined relative to mock