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Table 4 Factors associated with persistent pain: univariate and multivariate logistic regression models

From: Prevalence of persistent pain after breast cancer treatment by detection mode among participants in population-based screening programs

 

Univariate

Multivariatea

  

95 % CI

P-value

 

95 % CI

P-value

 

OR

Lower

Upper

 

OR

Lower

Upper

 

Detection method (n = 1045)

 Screening

Ref.

   

Ref.

   

 Interval

0.6

0.4

0.9

0.017

0.8

0.4

1.4

0.408

Age (n = 1045)

        

 50–54

Ref.

   

Ref.

   

 55–59

1.1

0.7

1.9

0.618

1.0

0.5

2.0

0.967

 60–64

0.9

0.5

1.5

0.632

0.7

0.3

1.6

0.424

 65–70

0.7

0.4

1.3

0.282

0.7

0.3

1.7

0.432

Charlson index (n = 1045)

 0

Ref.

   

Ref.

   

 1

2.3

1.5

3.7

<0.001

2.8

1.4

5.4

<0.01

  > =2

3.0

1.8

5.2

<0.001

4.5

2.1

9.5

<0.001

Histological type (n = 1038)

 In situ

Ref.

   

Ref.

   

 Ductal

6.4

1.5

26.4

<0.05

0.5

0.1

4.2

0.534

 Lobular

7.6

1.7

34.4

<0.01

1.1

0.5

2.7

0.784

 Other

4.1

0.8

20.5

0.082

0.6

0.2

2.1

0.422

Phenotype (n = 763)

        

 Luminal A

Ref.

   

Ref.

   

 Luminal B

0.5

0.3

1.1

0.074

0.6

0.3

1.3

0.219

 Her2

0.7

0.3

1.9

0.495

0.8

0.3

2.3

0.713

 Triple negative

1.0

0.5

2.2

0.903

1.1

0.5

2.6

0.800

Axillary treatmentb (n = 983)

 Only SLNB

Ref.

   

Ref.

   

 ALND

2.2

1.3

3.7

<0.05

2.0

1.0

4.0

<0.05

Neoadjuvant treatment (n = 1045)

 No

Ref.

   

Ref.

   

 Yes

0.5

0.2

1.1

0.095

0.4

0.1

1.3

0.132

Chemotherapy after surgery (n = 1018)

 

 No

Ref.

   

Ref.

   

 Yes

1.8

1.2

2.8

<0.01

1.4

0.7

2.5

0.334

  1. aN = 704 cases were included in the multivariate analysis. The multivariate logistic regression model included the following variables: detection method, age, Charlson index, histological type, phenotype, axillary treatment, neoadjuvant treatment and chemotherapy after surgery
  2. bSLNB: sentinel lymph node biopsy. In this category only women with SLNB performed were inluded. ALND: axillary lymph node dissection. This category includes women with only ALND performed and women with SLNB and ALND