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Table 2 Association between BMI and clinical-molecular features (N = 54)

From: Body mass index modifies the relationship between γ-H2AX, a DNA damage biomarker, and pathological complete response in triple-negative breast cancer

 

BMI

Chi2 Test

<25

≥25

p-value

N (%)

N (%)

 

Age at diagnosis

  < 49

20 (80.0)

5 (20.0)

0.002

  ≥ 49

11 (37.9)

18 (62.1)

 

Stage

 II

12 (66.7)

6 (33.3)

0.331

 III

19 (52.8)

17 (47.2)

 

Grade

 1–2

13 (59.1)

9 (40.9)

0.836

 3

18 (56.3)

14 (43.8)

 

Ki-67

 Low

15 (60.0)

10 (40.0)

0.721

 High

16 (55.2)

13 (44.8)

 

Chemotherapy

 Sequential

27 (57.4)

20 (42.6)

0.999a

 Concomitant

4 (57.1)

3 (42.9)

 

pCR

 No

19 (51.4)

18 (48.6)

0.184

 Yes

12 (70.6)

5 (29.4)

 

γ-H2AX

 Low

16 (64.0)

9 (36.0)

0.363

 High

15 (51.7)

14 (48.3)

 

pChk1

 Neg

12 (75.0)

4 (25.0)

0.090

 Pos

19 (50.0)

19 (50.0)

 
  1. aFisher’s Exact Test