Table 6 Analysis of metabolic variables with the components of metabolic syndrome at 6-months
Outcome variables | Fat percentage Change tertiles (values) | HOMA-IR Change tertiles (values) | Adiponectin Change tertile (values) | Leptin Change tertile (values) | Leptin adiponectin ratio tertile (values) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Decreased (−5.9 – −0.7) | Increased (1.3–5.6) | Decreased (−7.2–0.2) | Increased (1.8–7.3) | Decreased (−55.6 – −3.2) | Increased (2.1–21.9) | Decreased (−13.4 – −0.4) | Increased (2.7–17.5) | Decreased (−1.1 – −0.01) | Increased (0.1–1.5) | |
MS | ||||||||||
Waist circumference (cm) | ||||||||||
Coeficient | −3.8 | 0.6 | −0.1 | 2.5 | −0.3 | 0.6 | −0.1 | 2.7 | −1.5 | 2.5 |
95% CI | −6.2;-1.4 | −1.7;2.8 | −2.4; 2.3 | 0.1; 4.9 | −2.9; 2.4 | −2.2; 3.3 | −2.6; 2.5 | 0.1; 5.3 | −3.9; 0.9 | 0.1; 5.0 |
P | 0.003 | 0.623 | 0.950 | 0.041 | 0.850 | 0.668 | 0.963 | 0.041 | 0.218 | 0.042 |
Blood Pressure (mmHg) | ||||||||||
Systolic BP | ||||||||||
Coeficient | 0.1 | −6.8 | 5.1 | 6.7 | −3.5 | −4.0 | −3.5 | −1.7 | −7.3 | −5.4 |
95% CI | −9.2; 9.5 | −15.5;1.9 | −2.8; 13.1 | −1.3; 14.6 | −12.3; 5.3 | −12.8; 4.8 | −12.5; 5.6 | −10.9; 7.5 | −16.1; 1.6 | −14.3; 3.6 |
P | 0.975 | 0.123 | 0.202 | 0.098 | 0.425 | 0.361 | 0.447 | 0.709 | 0.104 | 0.235 |
Diastolic BP | ||||||||||
Coeficient | −5.6 | −7.7 | 6.1 | 3.6 | −2.9 | 2.2 | −5.1 | −0.2 | −3.4 | −3.5 |
95% CI | −13.9; 2.6 | −15.3;-0.0 | −1.1; 13.3 | −3.5; 10.8 | −10.3; 4.5 | −5.1; 9.6 | −12.6; 2.4 | −7.9; 7.4 | −11.1; 4.2 | −11.3; 4.2 |
P | 0.175 | 0.049 | 0.093 | 0.312 | 0.433 | 0.542 | 0.180 | 0.955 | 0.375 | 0.366 |
Glucose | ||||||||||
Coeficient | 0.3 | 1.9 | −5.5 | 5.1 | −2.0 | −1.7 | −6.9 | 1.7 | −5.9 | 1.5 |
95% CI | −6.4; 6.9 | −4.4; 8.1 | −10.4; −0.7 | 0.2; 10.0 | −7.9; 4.0 | −7.8; 4.4 | −12.3; -1.5 | −3.7;7.2 | −11.5; 0.4 | −4.1; 7.2 |
P | 0.936 | 0.549 | 0.027 | 0.043 | 0.509 | 0.568 | 0.013 | 0.529 | 0.037 | 0.590 |
Triglycerides | ||||||||||
Coeficient | −3.8 | −5.4 | −3.6 | 30.0 | 9.4 | 1.7 | −8.9 | 2.9 | −40.7 | −10.8 |
95% CI | −37.7; 30.2 | −37.6; 26.8 | −31.5; 24.3 | 1.7; 58.3 | −22.2; 41.0 | −30.5; 33.8 | −41.1; 23.2 | −29.8; 35.5 | −70.4; −11.1 | −40.9; 19.4 |
P | 0.823 | 0.738 | 0.797 | 0.038 | 0.551 | 0.918 | 0.579 | 0.861 | 0.008 | 0.476 |
HDL-C | ||||||||||
Coeficient | 0.6 | −1.8 | 2.4 | 3.6 | −8.3 | −0.5 | 1.0 | 3.0 | 2.6 | 0.3 |
95% CI | −7.1; 8.4 | −9.0; 5.4 | −4.2; 9.0 | −3.2; 10.4 | −14.5; −2.1 | −6.9; 5.9 | −6.0; 8.0 | −4.2; 10.2 | −4.4; 9.6 | −6.9; 7.6 |
P | 0.867 | 0.620 | 0.469 | 0.288 | 0.010 | 0.886 | 0.770 | 0.401 | 0.453 | 0.926 |
Adipokines | ||||||||||
Adiponectin | ||||||||||
Coeficient | 0.1 | −3.9 | 5.8 | 2.5 | - | - | −1.2 | −2.4 | - | - |
95% CI | −4.0; 4.8 | −9.0; 1.3 | 1.3; 10.3 | −2.3; 7.3 | −6.1; 3.8 | −7.4; 2.6 | ||||
P | 0.980 | 0.138 | 0.013 | 0.298 | 0.639 | 0.332 | ||||
Leptin | ||||||||||
Coeficient | 0.3 | 1.4 | −1.8 | 1.1 | 2.8 | 3.5 | - | - | - | - |
95% CI | −4.3; 4.9 | −2.9; 5.6 | −5.5; 1.9 | −2.8; 5.0 | −0.8; 6.5 | −0.2; 7.1 | ||||
P | 0.895 | 0.511 | 0.331 | 0.569 | 0.130 | 0.063 | ||||
Insulin resistance | ||||||||||
Fasting insulin (mμ/mL) | ||||||||||
Coeficient | −6.9 | 0.1 | - | - | −1.1 | −6.3 | −4.1 | 2.5 | −7.6 | 2.4 |
95% CI | −12.7; -1.1 | −5.8; 6.0 | −7.8; 5.7 | −13.2; 0.6 | −11.1; 2.9 | −4.6; 9.6 | −14.1; −1.1 | −4.3; 9.0 | ||
P | 0.020 | 0.978 | 0.753 | 0.072 | 0.241 | 0.480 | 0.023 | 0.476 | ||
HOMA-IR | ||||||||||
Coeficient | 1.8 | 1.7 | - | - | −0.4 | −1.7 | −1.1 | 0.9 | −2.2 | 0.8 |
95% CI | 0.1; 3.4 | 0.1; 3.4 | −2.2; 1.5 | −3.6; 0.2 | −3.1; 0.8 | −1.0; 2.9 | −3.9; -0.4 | −1.0; 2.6 | ||
P | 0.033 | 0.043 | 0.708 | 0.083 | 0.237 | 0.345 | 0.017 | 0.387 | ||