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Fig. 2 | BMC Cancer

Fig. 2

From: In search of druggable targets for GBM amino acid metabolism

Fig. 2

Detection of 34 proteins by immunohistochemistry (IHC) in high grade gliomas. The left side represents proteins expressed at levels less than or equal to levels in normal brain tissue. The right side shows IHC data for proteins expressed at levels greater than levels in normal brain tissue. The x-axis corresponds to the number of samples for each gene. Color codes indicate the intensity of protein expression for a given gene (as shown on legend). For example, for PHDGH (phosphoglycerate dehydrogenase) there were 11 samples -- 8 showed high expression, and 3 showed low expression. Left upper illustration exemplifies IHCs for couple of proteins. Abbreviations are as in Table 1. There is less overt clustering in the right upper and left lower quadrants compared to results in Fig. 1, because gene and protein over-expression match only in part

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