Fig. 3From: IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancerActivation of IGF pathway in bladder tumor is correlated with expression of some components of this pathway. a RPPA signal for phosphorylated IGF1R/INSR by tumor stages; b Spearman’s coefficient for the correlations between mRNA levels for IGF receptors, ligands, and binding proteins and the phosphorylated IGF1R/INSR RPPA signal; c heat map for the expression of IGF receptor, ligand, and binding protein genes in tumors, in decreasing order of phosphorylated IGF1R/INSR RPPA signal in the FBLAD-Exon dataset. Color intensity (blue-red scale) is centered on the mean value for expression in normal bladder samplesBack to article page