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Table 4 Associations between HSV and HPV, and their associations with cervical cancer-NHANES 2003–2010

From: Seropositivity to herpes simplex virus type 2, but not type 1 is associated with cervical cancer: NHANES (1999–2014)

Dependent variable

Independent variable

aOR

(95% CI)

P value

HPV16or18a

HSV1

1.03

(0.84–1.27)

0.75

HPV16or18a

HSV2

2.49

(1.96–3.16)

<0.01

Cervical cancera

HPV16or18

2.26

(1.14–4.45)

0.02

Cervical cancera

HSV2

2.17

(1.28–3.66)

0.00

Cervical cancerb

HSV2

1.90

(1.09–3.34)

0.02

  1. Abbreviations: HSV1, herpes simplex virus type 1; HSV2, herpes simplex virus type 2; HPV16or18, human papillomavirus type 16 or 18; aOR, Adjusted odds ratio; CI, confidence interval; NHANES, National Health and Nutrition Examination Survey
  2. aModel was adjusted for age, education, race, poverty income ratio, body mass index, smoking status, alcohol-use status and HIV status
  3. bModel was further adjusted for HPV status
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BMC Cancer

ISSN: 1471-2407

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