Table 1 Patient Demographics- all study patients
All number (n = 654) (%) | Early (n = 289) | Late (n = 365) | p | |
|---|---|---|---|---|
Age, mean (SD) | 64.9 | 64.9 (9.5) | 66.3 (9.0) | 0.03 |
Male, n (%) | 539 (82.4) | 239 (82.7) | 300 (82.2) | |
Tumor location | 0.01 | |||
Cervical, n (%) | 14 (2.1) | 7 (2.4) | 7 (1.9) | |
Upper, n (%) | 76 (12) | 40 (14) | 36 (9.9) | |
Middle, n (%) | 344 (53) | 131 (45) | 213 (58) | |
Lower, n (%) | 197 (30) | 100 (35) | 97 (27) | |
Abdominal, n (%) | 23 (3.5) | 11 (3.8) | 12 (3.3) | |
Histologic findings | 0.05 | |||
Squamous cell carcinoma, n (%) | 616 (94) | 271 (94) | 345 (95) | |
Adenocarcinoma, n (%) | 14 (2.1) | 4 (1.4) | 10 (2.7) | |
Adenosquamous carcinoma, n (%) | 7 (1.1) | 2 (0.7) | 5 (1.4) | |
Carcinosarcoma, n (%) | 6 (0.9) | 1 (0.3) | 5 (1.4) | |
Basaloid cell carcinoma, n (%) | 5 (0.8) | 4 (1.4) | 1 (0.3) | |
Small cell carcinoma, n (%) | 4 (0.6) | 4 (1.4) | 0 (0) | |
Neuroendocrine cell carcinoma, n (%) | 1 (0.2) | 0 (0) | 1 (0.3) | |
Malignant melanoma, n (%) | 1 (0.2) | 0 (0) | 1 (0.3) | |
pTNM Stage | 0.00 | |||
Stage IA, n (%) | 215 (33) | 68 (24) | 147 (40) | |
Stage IB, n (%) | 27 (4.1) | 12 (4.2) | 15 (4.1) | |
Stage IIA, n (%) | 72 (11) | 43 (15) | 29 (7.9) | |
Stage IIB, n (%) | 73 (11) | 29 (10) | 44 (12) | |
Stage IIIA, n (%) | 99 (15) | 45 (16) | 54 (15) | |
Stage IIIB, n (%) | 57 (8.7) | 30 (10) | 27 (7.4) | |
Stage IIIC, n (%) | 49 (7.5) | 27 (9.3) | 22 (6.0) | |
Stage IV, n (%) | 62 (9.5) | 35 (12) | 27 (7.4) | |
Neoadjuvant therapy | <0.001 | |||
None, n (%) | 185 (28) | 151 (52) | 34 (9.3) | |
Chemotherapy, n (%) | 337 (52) | 39 (13) | 298 (82) | |
Chemo-radiation, n (%) | 129 (20) | 97 (34) | 32 (8.8) | |
Radiation, n (%) | 3 (0.5) | 2 (0.7) | 1 (0.3) | |
Pleural adhesions | 0.71 | |||
Yes, n (%) | 206 (32) | 88 (30) | 118 (32) | |
No, n (%) | 448 (69) | 201 (70) | 247 (68) | |
Number of Lymphadenectomy Fields | 0.64 | |||
Two, n (%) | 448 (69) | 201 (70) | 247 (68) | |
Three, n (%) | 206 (32) | 88 (30) | 118 (32) | |
Abdominal Procedure | <0.001 | |||
Hand Assisted Laparoscopic Surgery, n (%) | 558 (85) | 205 (71) | 353 (97) | |
Laparotomy, n (%) | 96 (15) | 84 (29) | 12 (3.3) | |
Reconstruction Conduit | 0.01 | |||
Gastric tube, n (%) | 621 (95) | 272 (94) | 349 (96) | |
Right colon, n (%) | 22 (3.4) | 7 (2.4) | 15 (4.1) | |
Jejunum, n (%) | 9 (1.4) | 8 (2.8) | 1 (0.3) | |
Ileum, n (%) | 2 (0.3) | 2 (0.7) | 0 (0) | |
Reconstruction Route | 0.01 | |||
Retrosternal, n (%) | 641 (98) | 280 (97) | 361 (99) | |
Posterior mediastinal, n (%) | 13 (2.0) | 9 (3.1) | 4 (1.1) | |
Anastomosis Site | 0.02 | |||
Cervical, n (%) | 640 (98) | 277 (96) | 363 (99) | |
Intrathoracic, n (%) | 14 (2.1) | 12 (4.2) | 2 (0.5) | |
Conversion to thoracotomy, n (%) | 3 (0.5) | 1 (0.3) | 2 (0.5) | 0.70 |