Table 1 List of 17 upregulated KEAP1-NRF2-CUL3 axis genes identified in HNSCC
Gene symbol | Description |
|---|---|
AKR1B10 | Aldo-keto reductase family 1 member B10 |
AKR1C1 | Aldo-keto reductase family 1 member C1 |
AKR1C2 | Aldo-keto reductase family 1 member C2 |
AKR1C3 | Aldo-keto reductase family 1 member C3 |
G6PD | Glucose-6-phosphate dehydrogenase |
GCLC | Glutamate-cysteine ligase catalytic subunit |
GCLM | Glutamate-cysteine ligase modifier subunit |
GSTM3 | Glutathione S-transferase mu 3 |
NTRK2 | Neurotrophic receptor tyrosine kinase 2 |
OSGIN1 | Oxidative stress induced growth inhibitor 1 |
RAB6B | RAB6B, member RAS oncogene family |
SLC7A11 | Solute carrier family 7 member 11 |
SPP1 | Secreted phosphoprotein 1 |
SRXN1 | Sulfiredoxin 1 |
TRIM16L | Tripartite motif containing 16-like |
TXNRD1 | Thioredoxin reductase 1 |
UCHL1 | Ubiquitin C-terminal hydrolase L1 |