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Fig. 6 | BMC Cancer

Fig. 6

From: FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-XL cell survival genes

Fig. 6

Inhibition of Bcl-2 anti-apoptotic family proteins decreases protective effects of FAM3B. a DU145 cells were treated with 1 ng/ml and 5 ng/ml TNF-α + 10 μM CHX and 10 μM ABT-737or 0.1 μM GX15–070 (OBTX) (b) a dose-dependent assay between 0.13 and 5 ng/ml TNF and 0.1 μM GX15–070 (OBTX). The results are expressed as means of three independent experiments and as relative percent of control cells or FAM3B cells respectively. Statistical differences were determined by Two-way Anova test. (# p < 0.001; & p < 0.01)

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BMC Cancer

ISSN: 1471-2407

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