Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Sequential decitabine and carboplatin treatment increases the DNA repair protein XPC, increases apoptosis and decreases proliferation in melanoma

Fig. 3

Combined decitabine and carboplatin treatment induces XPC expression in melanoma. Melanoma cell lines were treated with 0.26 μM decitabine for 72 h, 8 μg/mL carboplatin for 48 h, or both in sequential combination. XPC expression was quantified by qPCR in response to single and combined treatments (a). Baseline expression with no treatment was used as a control. Significance displayed between carboplatin alone and combination treatment. Data represent mean of triplicate experiment, bars = SEM. **p < 0.01, ***p < 0.001. Western blot (b) of XPC after single and combined decitabine (0.26 μM) and carboplatin (8 μg/mL) treatment. Numbers represent fold change from baseline. Data was normalised to loading control (TATA BP)

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us