Fig. 4
From: ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer
miR-590-3p repressed the proliferation by targeting GOLPH3. a MTS proliferation assay showed overexpression of GOLPH3 could rescue miR-590-3p repressing cell proliferation during 24, 48, 72 h. Data shown are means ± SD (n = 3), **P < 0.01. b BrdU incorporation assay in rescue experiment. Data shown are means ± SD (n = 3), **P < 0.01. c Flow cytometry assay in rescue experiment. Data shown are means ± SD (n = 5). d Expression level of mRNA of cell cycle-related genes. Data shown are means ± SD (n = 3). **P < 0.01 versus the corresponding control