Fig. 4

Increased Foxp3⁺ T cell infiltration in gallbladder cancer tissues correlates with poor patient survival. Kaplan-Meier survival curves for patients with positive or negative Foxp3⁺ T cell infiltration in primary tumors for (a) All stages; (b) Early stages (0 and I); and (c) Advanced stages (II, IIIA, IIIB, and IV). Negative Foxp3⁺ T cell infiltration was significantly associated with prolonged survival in all stages and early stage patients (log-rank p = 0.03 and 0.04, respectively). The survival proportions of patients after GBC diagnosis in a 5-year term are shown to the right of the curves