Table 2 Characteristics of ovarian cancer patients visiting HCP for BRCA1 or BRCA2 testing in British Columbia by serous status, 2001–2013
Serous ovarian cancer N = 581 | Endometrioid or clear cell ovarian cancers N = 134 | p-value | |
|---|---|---|---|
Age at diagnosis | 60.0 ± 11.1 | 51.3 ± 11.0 | < 0.001 |
Year of diagnosis | 2007.9 ± 4.3 | 2005.3 ± 5.2 | < 0.001 |
Age at time of first visit to HCP | 62.3 ± 11.4 | 55.1 ± 11.3 | < 0.001 |
Year of first visit to HCP | 2009.6 ± 3.4 | 2008.4 ± 3.3 | < 0.001 |
Index test | |||
Index | 564 (97.1) | 129 (96.3) | |
Carrier | 17 (2.9) | 5 (3.7) | 0.237 |
Proband status | |||
Yes | 527 (90.7) | 116 (86.6) | |
No | 54 (9.3) | 18 (13.4) | 0.151 |
Number of first degree relative | |||
0–3 | 423 (72.8) | 97 (72.4) | |
4–6 | 122 (21.0) | 32 (23.9) | |
7+ | 36 (6.2) | 5 (3.7) | 0.455 |
Number of second degree relatives | |||
0–3 | 257 (44.2) | 58 (43.3) | |
4–6 | 189 (32.5) | 53 (40.0) | |
7+ | 135 (23.2) | 23 (17.1) | 0.180 |
Number of third degree relatives | |||
0–3 | 303 (52.2) | 62 (46.3) | |
4–6 | 164 (28.2) | 38 (28.4) | |
7+ | 114 (19.6) | 34 (25.4) | 0.290 |
Number of fourth degree relatives | |||
0–3 | 545 (93.8) | 122 (91.0) | |
4–6 | 14 (2.4) | a < 5% | |
7+ | 22 (3.8) | a < 5% | 0.323 |
BRCA1 or BRCA2 positive | 124 (21.3) | 10 (7.5) | < 0.001 |