Table 1 Univariate analysis of patient demographics, clinical characteristics and treatment by age group
N | Age 18–44 years (%) | Age 45–59 years (%) | Age ≥ 60 years (%) | p-value | |
|---|---|---|---|---|---|
Gender | |||||
Male | 3576 | 1347 (18.5) | 1290 (24.5) | 939 (29.8) | < 0.001 |
Female | 12,099 | 5915 (81.5) | 3971 (75.5) | 2213 (70.2) | |
Tumor size | |||||
1 to < 2 cm | 6374 | 2909 (40.1) | 2325 (44.2) | 1140 (36.2) | < 0.001 |
≥ 2 to < 3 cm | 3953 | 1918 (26.4) | 1305 (24.8) | 730 (23.2) | |
≥ 3 to < 5 cm | 3189 | 1552 (21.4) | 955 (18.1) | 682 (21.6) | |
≥ 5 cm | 1288 | 547 (7.5) | 376 (7.2) | 365 (11.6) | |
Unknown | 871 | 336 (4.6) | 300 (5.7) | 235 (7.5) | |
Stage | |||||
Localized | 8686 | 3922 (54.0) | 3.098 (58.9) | 1666 (52.9) | < 0.001 |
Regional | 6138 | 3106 (42.8) | 1925 (36.6) | 1107 (35.1) | |
Remote | 825 | 224 (3.1) | 228 (4.3) | 373 (11.8) | |
Unknown | 26 | 10 (0.1) | 10 (0.2) | 6 (0.2) | |
Surgery | |||||
Completion thyroidectomy (TTX) | 777 | 388 (5.3) | 272 (5.2) | 117 (3.7) | < 0.001 |
Thyroid lobectomy | 1950 | 794 (10.9) | 670 (12.7) | 486 (15.4) | |
Total TTX | 10,071 | 4577 (63.0) | 3503 (66.6) | 1991 (63.2) | |
Total TTX with cervical lymphadenectomy | 2877 | 1503 (20.7) | 816 (15.5) | 558 (17.7) | |
Radioactive iodine | |||||
Yes | 9868 | 4673 (64.3) | 3321 (63.1) | 1874 (59.4) | < 0.001 |
External beam radiation | |||||
Yes | 193 | 62 (0.8) | 51 (1.0) | 80 (2.5) | < 0.001 |
Hospital thyroidectomy volume | |||||
< 15 yearly | 3545 | 1632 (22.5) | 1180 (22.4) | 733 (23.3) | 0.081 |
15 to < 30 yearly | 4433 | 2057 (28.3) | 1484 (28.2) | 892 (28.3) | |
30 to < 55 yearly | 3953 | 1778 (24.5) | 1341 (25.5) | 834 (26.5) | |
55+ yearly | 3744 | 1795 (24.7) | 1256 (23.9) | 693 (22.0) | |
# Of comorbidities | |||||
0 | 13,200 | 6591 (90.8) | 4363 (82.9) | 2243 (71.3) | < 0.001 |
1 | 2180 | 630 (8.7) | 798 (15.2) | 752 (23.9) | |
2 + | 295 | 41 (0.60) | 100 (1.9) | 154 (4.9) | |
Race | |||||
Asian/Pacific Islander | 2608 | 1157 (15.9) | 864 (16.4) | 587 (18.6) | < 0.001 |
Black | 527 | 193 (2.7) | 209 (4.0) | 125 (4.0) | |
Hispanic | 4277 | 2323 (32.0) | 1287 (24.5) | 667 (21.2) | |
White | 7707 | 3316 (45.6) | 2727 (51.8) | 1664 (52.8) | |
Other | 556 | 273 (3.8) | 174 (3.3) | 109 (3.5) | |
Insurance | |||||
Medicaid/indigent | 1494 | 757 (10.4) | 539 (10.2) | 198 (6.3) | < 0.001 |
Medicare | 2002 | 76 (1.0) | 175 (3.3) | 1751 (55.5) | |
Private/HMO | 11,738 | 6209 (85.5) | 4380 (83.2) | 1149 (36.4) | |
VA/Federal | 146 | 80 (1.1) | 46 (0.9) | 20 (0.6) | |
Other/unknown | 295 | 140 (1.9) | 121 (2.3) | 34 (1.1) | |
Nci hospital | |||||
Yes | 2358 | 1137 (15.7) | 773 (14.7) | 448 (14.2) | 0.114 |