Table 2 Multivariable Cox-proportional hazards analysis of predictors of 5-year disease-specific survival
HR (95% CI) | p-value | |
|---|---|---|
Stage | ||
Regional | 8.7 (4.8–15.9) | < 0.001 |
Metastatic | 40.9 (22.5–74.5) | < 0.001 |
Tumor size | ||
≥ 2 to < 3 cm | 2.0 (1.1–3.6) | 0.021 |
≥ 3 to < 5 cm | 3.7 (2.2–6.3) | < 0.001 |
≥ 5 cm | 6.5 (3.8–11.2) | < 0.001 |
Unknown | 5.0 (2.7–9.3) | < 0.001 |
Radioactive iodine | ||
Yes | 0.50 (0.38–0.67) | < 0.001 |
Hospital volume (vs. average < 15 thyroidectomies yearly) | ||
15 to < 30 | 1.11 (0.76–1.63) | 0.574 |
30–55 | 0.81 (0.55–1.21) | 0.311 |
55+ | 1.16 (0.78–1.72) | 0.452 |
Surgery performed (vs. thyroid lobectomy) | ||
Completion thyroidectomy | 0.23 (0.03–1.73) | 0.156 |
Total thyroidectomy | 0.70 (0.47–1.04) | 0.078 |
Total thyroidectomy with cervical lymphadenectomy | 1.10 (0.72–1.66) | 0.660 |
Race (vs. Non-Hispanic White) | ||
Non-Hispanic Black | 0.71 (0.26–1.93) | 0.501 |
Hispanic | 1.01 (0.73–1.42) | 0.915 |
Asian/Pacific Islander | 0.73 (0.49–1.08) | 0.120 |
Other race/Unknown | 1.42 (0.76–2.68) | 0.274 |
Age | ||
45–59 | 16.43 (6.55–41.18) | < 0.001 |
≥ 60 | 38.16 (15.08–96.57) | < 0.001 |
Gender | ||
Female | 1.02 (0.76–1.36) | 0.890 |
Comorbidities (vs. none) | ||
1 | 0.89 (0.64–1.24) | 0.493 |
2 or more | 0.77 (0.39–1.53) | 0.457 |
Insurance (vs. private/hmo) | ||
Medicare | 1.20 (0.83–1.73) | 0.334 |
Medicaid/Indigent | 1.40 (0.87–2.25) | 0.160 |
County/Tricare/Military/VA | 0.81 (0.11–6.07) | 0.839 |
Not Insured/Other/Unknown | 1.70 (0.53–5.45) | 0.375 |