Table 3 Multivariable Cox-proportional hazards analysis of predictors of 10- year disease-specific survival
HR (95% CI) | p-value | |
|---|---|---|
Stage | ||
Regional | 7.3 (4.6–11.6) | < 0.001 |
Metastatic | 31.0 (19.5–49.3) | < 0.001 |
Tumor size | ||
≥ 2 to < 3 cm | 1.8 (1.1–2.8) | 0.011 |
≥ 3 to < 5 cm | 2.8 (1.8–4.2) | < 0.001 |
≥ 5 cm | 5.7 (3.7–8.7) | < 0.001 |
Unknown | 3.3 (2.0–5.5) | < 0.001 |
Radioactive iodine | ||
Yes | 0.6 (0.5–0.7) | < 0.001 |
Hospital volume (vs. average < 15 thyroidectomies yearly) | ||
15 to < 30 | 1.1 (0.8–1.5) | 0.488 |
30–55 | 0.8 (0.6–1.2) | 0.297 |
55+ | 1.1 (0.8–1.5) | 0.658 |
Surgery performed (vs. thyroid lobectomy) | ||
Completion thyroidectomy | 0.4 (0.1–1.4) | 0.179 |
Total thyroidectomy | 0.8 (0.5–1.1) | 0.123 |
Total thyroidectomy with cervical lymphadenectomy | 1.2 (0.8–1.7) | 0.305 |
Race (vs. non-hispanic white) | ||
Non-Hispanic Black | 0.7 (0.3–1.7) | 0.491 |
Hispanic | 1.0 (0.8–1.4) | 0.713 |
Asian/Pacific Islander | 0.9 (0.6–1.2) | 0.543 |
Other race/Unknown | 1.6 (0.9–2.7) | 0.093 |
Age | ||
45–59 | 12.2 (6.3–23.6) | < 0.001 |
≥ 60 | 29.7 (15.2–58.2) | < 0.001 |
Gender | ||
Female | 0.8 (0.6–1.1) | 0.157 |
Comorbidities (vs. none) | ||
1 | 0.9 (0.7–1.2) | 0.486 |
2 or more | 0.8 (0.4–1.4) | 0.429 |
Insurance (vs. private/hmo) | ||
Medicare | 1.2 (0.9–1.7) | 0.191 |
Medicaid/Indigent | 1.4 (0.9–2.0) | 0.126 |
County/Tricare/Military/VA | 1.3 (0.3–5.5) | 0.719 |
Not Insured/Other/Unknown | 2.0 (0.7–5.6) | 0.168 |