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Table 1 ILC populations surface markers

From: Activated innate lymphoid cell populations accumulate in human tumour tissues

Studied populations

Definition

ILC1

CD45+ Lin- CD56- CD127+ c-Kit- CRTH2-

ILC2

CD45+ Lin- CD56- CD127+ c-Kit−/+ CRTH2+

ILC3

CD45+ Lin- CD56- CD127+ c-Kit+ CRTH2-

NK cells

CD45+ Lin- CD56+

  1. Lineage markers: CD3, CD14, CD19, CD11c, CD11b, CD56, IL-3R, FcεRI, TCRαβ and TCRγδ. ILC were divided into 3 groups based on expression of cell surface markers. ILC1 cells were identified as Lineage negative, CD45+, CD127+, CD56−, CRTH2− and c-Kit−. Group 2 ILC were negative for lineage markers, CD56 and expressed CRTH2 and CD127. Group 3 ILC expressed c-Kit, CD45 and CD127, did not express CD56 and CRTH2
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BMC Cancer

ISSN: 1471-2407

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