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Table 3 Medications for HBV and HCV patients in the study period (grouped by use of angiotensin converting enzyme inhibitors [ACEIs] or angiotensin receptor blockers [ARBs] used in the initial 6 months after index date)

From: Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in chemoprevention of hepatocellular carcinoma: a nationwide high-risk cohort study

  

HBV patients

  

HCV patients

 

Variables

All

Initial exposure

Initial non-exposure

All

Initial exposure

Initial non-exposure

n

7724

3575

4149

7873

3349

4524

ACEI/ARB

      

 DDD

1.0 (0.7–1.3)

1.0 (0.7–1.3)

0.9 (0.5–1.1)

1.0 (0.7–1.3)

1.0 (0.8–1.3)

0.9 (0.5–1.1)

 Duration (months)

36.4 (12.5–50.0)

41.8 (22.2–53.6)

18.3 (3.0–35.9)

38.9 (18.4–53.1)

46.4 (36.1–57.9)

22.7 (6.8–38.6)

Aspirin

      

 DDD

1.6 (0.9–2.0)

1.7 (1.0–2.0)

1.5 (0.9–1.9)

1.6 (0.9–1.9)

1.7 (1.0–2.0)

1.5 (0.9–1.9)

 Duration (months)

22.0 (3.3–44.5)

25.1 (4.9–45.5)

18.3 (1.5–42.4)

24.9 (4.9–46.9)

30.6 (7.1–48.6)

21.0 (3.1–45.3)

Metformin

      

 DDD

0.5 (0.3–0.7)

0.5 (0.3–0.7)

0.5 (0.3–0.6)

0.5 (0.3–0.6)

0.5 (0.3–0.7)

0.5 (0.3–0.6)

 Duration (months)

26.7 (7.3–44.6)

29.5 (8.9–45.3)

23.6 (5.8–43.6)

35.5 (13.7–50.3)

37.3 (17.6–49.7)

31.4 (10.0–50.8)

Statin

      

 DDD

0.5 (0.3–0.8)

0.5 (0.3–0.8)

0.5 (0.3–0.8)

0.5 (0.3–0.7)

0.5 (0.3–0.7)

0.5 (0.3–0.7)

 Duration (months)

23.3 (6.3–43.9)

25.7 (7.4–44.6)

20.7 (5.5–42.8)

20.0 (5.7–38.5)

22.5 (7.2–39.1)

17.4 (4.9–37.3)

  1. Data are median (Q1-Q3). DDD defined daily dose