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Fig. 2 | BMC Cancer

Fig. 2

From: A computational study of hedgehog signalling involved in basal cell carcinoma reveals the potential and limitation of combination therapy

Fig. 2

Sensitivity heat maps of the SMO network. Sensitivity was calculated in response to variations in SMO and PI3K activities on the xy-plane (left and right, respectively), combined with different levels of cAMP (as in Fig. 1) on the z-axis. The regions of high sensitivity between low and high SMO and PI3K activities (blue-red-yellow areas) correspond to a transition zone between low and high steady-state activity of tumour proliferation

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