Fig. 5From: Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular trapsChloroquine reverses hypercoagulability in pancreatic cancer. Representative TEG curves demonstrating orthotopically injected mice are hypercoagulable compared with sham controls (a). Treatment with CQ reverses the hypercoagulability on TEG as measured by coagulation index (b). The 90 day VTE rate for patients treated with 2 cycles of preoperative gemcitabine/abraxane + HCQ was 9.1% (n = 3 of 33) compared to 30% (n = 9 of 30) in patients treated with gemcitabine/abraxane alone (c, p = 0.053)Back to article page