Fig. 6
From: Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers
Expression of mucin 2 (MUC2) and mucin 1 (MUC1) in human CRCs. a, representative IHC of MUC2 in CRCs. Abundant MUC2 proteins were produced in normal crypts, while reduced or absent expression was observed in tumor sections. b, representative IHC of MUC1 in CRCs. Elevated MUC1 proteins were detected in tumor sections. All scale bars are 200Ā Ī¼m. c, differential expression of MUC1 and MUC2 in matched CRCs. IHC score (IS) of each staining was plotted with triangle (normal) and square (tumor) shaped boxes respectively. The mean and standard error (SEM) values are indicated by longer lines and shorter lines, respectively. The p-values were determined by Paired sample t test. d, correlation between MUC1 and Tn expression in human colorectal tumors. The IS of 20 tumors were plotted for MUC1 and Tn staining. The Pearsonās r was 0.0208, indicating no correlation between MUC1 and Tn antigen expression