Fig. 4From: Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatmentFunctional analysis of the effect of BKM120 and/or MEK162 at the indicate doses in HCT116 cells. (a) FACS profiles for EdU incorporation, propidium iodide staining (late apoptosis marker) and presence of cleaved caspase 3 (early apoptosis marker) and (b) the corresponding mean intensity values in the various experimental conditions. NT, not treatedBack to article page