Fig. 1

Representative Sp17 immunohistochemistry staining in ovarian tissue of serous histology. Examples of Sp17 protein expression in benign and malignant ovarian tissue demonstrating both positive and negative staining and intensity of Sp17 staining are shown. a) Serous cystadenoma showing tissue staining positive with strong expression of Sp17 in ciliated cells. b) Serous borderline tumor showing strong Sp17 expression. c) Grade 1 serous adenocarcinoma negative for Sp17 expression. d) Grade 1 serous adenocarcinoma showing strong Sp17 expression. e) Grade 3 serous adenocarcinoma negative for Sp17. f) Grade 3 serous adenocarcinoma demonstrating strong Sp17 staining. Stroma surrounding epithelial cells is negative