Elevated platelet count is a negative predictive and prognostic marker in locally advanced rectal cancer undergoing neoadjuvant chemoradiation: a retrospective multi-institutional study on 965 patients

Table 2 Multivariate analysis (Binary Logistic Regression) using complete pathological response (pCR) to neoadjuvant chemoradiation as dependent variable in 965 patients with locally advanced rectal cancer

	Reference	Odds Ratio	(CI 95%)	p
Age		0.99	0.98–1.01	0.497
Sex	Female	1.11	0.80–1.56	0.533
cT	I-II	0.58	0.34–0.99	0.045
cN	0	1.05	0.75–1.46	0.797
Platelets count	< 300 × 10⁹/L	0.51	0.34–0.75	0.001
Distance from anal verge	< 5 cms	1.48	1.06–2.08	0.022
Interval between CRT and Surgery	< 8 weeks	1.35	0.93–1.97	0.115

cT Clinical primary tumor stage, cN Clinical lymph node stage, CRT chemoradiation

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