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Table 2 Prior regimes of the mCRC patients in the German compassionate-use-program of FTD/TPI

From: Safety profile of trifluridine/tipiracil monotherapy in clinical practice: results of the German compassionate-use program for patients with metastatic colorectal cancer

Lead Substance of Combination Treatment (if applicable)

Number of Patients in the German FTD/TPI CUP

% of Patients in the German FTD/TPI CUP

Fluorouracil

220

97.35%

Irinotecan

223

98.67%

Oxaliplatin

199

88.05%

Bevacizumab

193

85.4%

Cetuximaba

76

33.63%

Panitumumaba

59

26.11%

Regorafenib

76

33.63%

Aflibercept

63

27.88%

Ramucirumab

4

1.77%

Mitomycin

17

7.52%

  1. asome patients received both EGFR antibodies
  2. One mCRC patient each received gemcitabine, carboplatin, pembrolizumab, nintedanib or niclosamide
  3. Abbreviations: EGFR, epithelial growth factor receptor; monoclonal antibodies, mabs; not available, n.a