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Table 3 Demographic and clinical characteristics of patients who started treatment with dose reduction

From: Prognostic factors for survival with nab-paclitaxel plus gemcitabine in metastatic pancreatic cancer in real-life practice: the ANICE-PaC study

Demographic characteristics

 Age, n (%)

(n = 68)

 

  < 65 years

 

33 (48.5%)

  65–79 years

 

14 (20.6%)

  ≥ 70 years

 

21 (30.9%)

 Sex, n (%)

(n = 68)

 

  Males

 

41 (60.3%)

  Females

 

27 (39.7%)

Clinical characteristics

 Weight loss > 10%, n (%)

(n = 66)

18 (27.3%)

 ECOG PS, n (%)

(n = 62)

 

  0–1

 

46 (74.2%)

  2-Mar

 

16 (25.8%)

 Karnofsky PS, n (%)

(n = 23)

 

  < 70

 

  70–80

 

13 (56.5%)

  90–100

 

10 (43.5%)

 Common comorbidities, n (%)

(n = 68)

 

  Hypertension

 

15 (22.1%)

  Diabetes

 

8 (11.8%)

  Dyslipemia

 

4 (5.9%)

 Hepatobiliary stent, n (%)

(n = 68)

10 (14.7%)

 Platelet count, median (IR)

(n = 57)

252.0 (172.0, 339.0)

 Bilirubin (mg/dL), median (IR)

(n = 58)

0.70 (0.51, 1.10)

 NLR, n (%)

(n = 55)

 

  > 3

 

29 (52.7%)

  ≤ 3

 

26 (47.3%)

 CA 19.9, n (%)

(n = 62)

 

  > 35

 

52 (83.9%)

  ≤ 35

 

10 (16.1%)

 Number of metastatic sites, n (%)

(n = 68)

 

  1–3

 

67 (98.5%)

  > 3

 

1 (1.5%)

 Concommitant treatment, n (%)

(n = 68)

 

  Analgesics

 

22 (32.4%)

  Corticosteroids

 

9 (13.2%)

  1. IR Interquartile range (percentile 25, percentile 75)
  2. anumber of evaluable patients (no-missing)