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Table 2 IC50 values of the isolated canine and human melanoma cell lines, 72 h after treatment with Dacarbazine, Vemurafenib and LY294002 (IC50 ± SEM, n = 6)

From: Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology

IC50 (μM)

 

A375

Sk-Mel28

Ocr_OCMM1X

Ocr_OCMM2X

Dacarbazine

202.4 ± 60,40

261.04 ± 31.55

> 400

> 400

Vemurafenib

0.54 ± 0.05

10.78 ± 3.29

37.44 ± 8.84

12.31 ± 0.85

LY294002

61.63 ± 16.85

26.56 ± 0.81

37.74 ± 9.6

32.39 ± 2.01

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BMC Cancer

ISSN: 1471-2407

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