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Fig. 2 | BMC Cancer

Fig. 2

From: MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

Fig. 2

MEF2 is integral in mediating the anti-proliferative effect of RENCA macrobeads. RENCA cells were transiently transfected with two-rounds of 1 μM non-targeting siRNA, MEF2a, MEF2b, MEF2d or combined MEF2a, b and d siRNAs (MEF2 pool) for 72 h followed by culture in naïve media or together with > 18 wk. RENCA macrobeads in a cell culture insert system for 5 days. Each column represents the mean absorbance value (n = 3) ± SD following neutral red staining, with growth inhibition calculated as the percent difference in absorbance between the indicated conditions. *p < 0.005 compared with naïve media

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BMC Cancer

ISSN: 1471-2407

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